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                      • Home
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                      • Tissue glue
                      • Histoacryl® LapFix Pack

                      Histoacryl® LapFix-Product Picture
                      Histoacryl® LapFix-Product Picture CW Enlargement
                      Histoacryl® LapFix Optilene® Mesh-Product Picture CW Enlargement
                      Histoacryl® LapFix-Product Picture Enlargement CW
                      Histoacryl® LapFix-Product Picture
                      Histoacryl® LapFix-Product Picture
                      Histoacryl® LapFix-Product Picture CW Enlargement
                      Histoacryl® LapFix Optilene® Mesh-Product Picture CW Enlargement
                      Histoacryl® LapFix-Product Picture Enlargement CW

                      Histoacryl® LapFix Pack
                      Atraumatic mesh fixation

                      Histoacryl® LapFix Pack is a tissue adhesive applicator for laparoscopic hernia repair surgeries. It consists of a Histoacryl® LapFix-Cannula, a Syringe Injekt® 2mL Luer Lock Solo and a Histoacryl® ampoule.

                      In recent years, atraumatic mesh fixation with tissue adhesive has increasingly become the method of choice. It is the recommended mesh fixation method by the International Hernia Society Guidelines for groin hernia management [1].

                       

                      Histoacryl® Mesh Fixation is…

                      Atraumatic

                      • Stand-alone fixation method in different hernia repair techniques [2-10]
                      • Rapid polymerization [11]
                      • Atraumatic method reported to be better tolerated by the patient than traditional fixation methods [2-7, 9, 10, 12]

                      Prevents complications

                      • Reduced risk of post-operative pain compared to traditional fixation methods [2-7, 9, 12]
                      • Faster return to work compared to traditional fixation methods. [2, 4, 8, 13]
                      • Lower or similar intra- and postoperative morbidity compared to traditional fixation methods. [2, 4, 7, 9, 12]
                      • Lower or similar rate of infections related to Histoacryl® than other techniques [2, 4-6, 12, 14]
                      • Similar recurrence rate than with traditional fixation methods [2-9, 12]

                      Easy to use

                      • Decreased surgery time compared to traditional fixation [4-6, 8, 12]
                      • Storage at <22 ºC [15]

                      Affordable

                      • Only necessary to apply few small drops to the desired fixing sites. [11,16]
                      • Lower price than tackers, fibrin glue or staples. [17]

                       

                      Read more

                      Histoacryl® LapFix Pack is a tissue adhesive applicator for laparoscopic hernia repair surgeries. It consists of a Histoacryl® LapFix-Cannula, a Syringe Injekt® 2mL Luer Lock Solo and a Histoacryl® ampoule.

                      In recent years, atraumatic mesh fixation with tissue adhesive has increasingly become the method of choice. It is the recommended mesh fixation method by the International Hernia Society Guidelines for groin hernia management [1].

                       

                      Histoacryl® Mesh Fixation is…

                      Atraumatic

                      • Stand-alone fixation method in different hernia repair techniques [2-10]
                      • Rapid polymerization [11]
                      • Atraumatic method reported to be better tolerated by the patient than traditional fixation methods [2-7, 9, 10, 12]

                      Prevents complications

                      • Reduced risk of post-operative pain compared to traditional fixation methods [2-7, 9, 12]
                      • Faster return to work compared to traditional fixation methods. [2, 4, 8, 13]
                      • Lower or similar intra- and postoperative morbidity compared to traditional fixation methods. [2, 4, 7, 9, 12]
                      • Lower or similar rate of infections related to Histoacryl® than other techniques [2, 4-6, 12, 14]
                      • Similar recurrence rate than with traditional fixation methods [2-9, 12]

                      Easy to use

                      • Decreased surgery time compared to traditional fixation [4-6, 8, 12]
                      • Storage at <22 ºC [15]

                      Affordable

                      • Only necessary to apply few small drops to the desired fixing sites. [11,16]
                      • Lower price than tackers, fibrin glue or staples. [17]

                       

                      References

                      [1] HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018;22(1):1-165.
                      [2] Helbling C, Schlumpf R. Sutureless Lichtenstein: first results of a prospective randomised clinical trial. Hernia. 2003;7(2):80-4. 
                      [3] Testini M, Lissidini G, Poli E, Gurrado A, Lardo D, Piccinni G. A single-surgeon randomized trial comparing sutures, N-butyl-2-cyanoacrylate and human fibrin glue for mesh fixation during primary inguinal hernia repair. Can J Surg. 2010;53(3):155-60.
                      [4] Kim-Fuchs C, Angst E, Vorburger S, Helbling C, Candinas D, Schlumpf R. Prospective randomized trial comparing sutured with sutureless mesh fixation for Lichtenstein hernia repair: long-term results. Hernia. 2012;16(1):21-7.
                      [5] Hoyuela C, Juvany M, Carvajal F, Veres A, Troyano D, Trias M, et al. Randomized clinical trial of mesh fixation with glue or sutures for Lichtenstein hernia repair. Br J Surg. 2017;104(6):688-94.
                      [6] Vega L, Oh-Uiginn K, Carmona D, Salazar D, Rodriguez R, Janafse H, et al. Cyanoacrylate mesh fixation in Lichtenstein inguinal hernia repair. Does it have advantages? Glob J Surg. 2019;7(1):1–4 
                      [7] Mathur DRK, Baghel DH, Pancholi DA. To evaluate the efficacy of N-butyl cyanoacrylate glue for mesh fixation in laparoscopic inguinal hernia repair. Int J Surg Sci. 2020;4(1):197–9.
                      [8] Juvany M, Guillaumes S, Hoyuela C, Bachero I, Trias M, Ardid J, et al. Results of a Prospective Cohort Study on Open Rives Technique of the Midline Incisional Hernia: Midline Closure and Mesh Overlap. Surg Innov. 2022;29(3):321–8.
                      [9] Yu CC, Chen YT, Huang CS, Chueh SJ, Lo CW, Tsai YC. A comprehensive study comparing tack and glue mesh fixation in laparoscopic total extraperitoneal repair for adult groin hernias. Surg Endosc. 2020;34(10):4486-93.
                      [10] Liew W, Wai YY, Kosai NR, Gendeh HS. Tackers versus glue mesh fixation: an objective assessment of postoperative acute and chronic pain using inflammatory markers. Hernia. 2017;21(4):549-54.
                      [11] IFU Histoacryl MDR
                      [12] Shukla A, Mathur RK, Sheikh Z, Jain V. N-Butyl-2-Cyanoacrylate Glue versus Suture for Mesh Fixation in Open Inguinal Hernioplasty. J Evol Med Dent Sci. 2019;8(48):3575–8. 
                      [13] Raafat A, Osman G. Histoacryl Glue versus Polypropylene Suture Mesh Fixation in Lichtenstein Inguinal Hernioplasty. Int. J. of Life Sciences, 2018;6(1):1-5.
                      [14] Kukleta JF, Freytag C, Weber M. Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long-term biocompatibility in over 1,300 mesh fixations. Hernia. 2012;16(2):153-62.
                      [15] Internal Report_RDR/DID/CHM/SLE/19078 – Real Time Stability Study on Histoacryl® –22 ºc
                      [16] Internal Report_RDR/DID/CHM/SLE/21182 - Determination of Adhesive Strength – Mesh Fixation with Histoacryl 
                      [17] NICE. Cyanoacrylate glue for hernia mesh fixation. Medtech innovation briefing [MIB301]. 2022